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저널 연구

2023년

Research

Dec 2023

J Control Release

Volume 366

Inhibition of protein-protein interactions using biodegradable depsipeptide nanoassemblies

Choi SH, Hwang HS, Han S, Eom H, Choi JS, Han S, Lee D, Lee SY, Koo H, Kwon HJ*, Lim YB*

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Research

Dec 2023

Biomed Pharmacother

Volume 168,

Issue 115776

Inhibition of chloride intracellular channel protein 1 (CLIC1) ameliorates liver fibrosis phenotype by activating the Ca2+-dependent Nrf2 pathway

Ko M, Jung HY, Lee D, Jeon J, Kim J, Baek S, Lee JY, Kim JY, Kwon HJ*

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Research

Nov 2023

J Proteome Res.

Volume 23, Issue 1

NDUFA12 as a Functional Target of the Anticancer Compound Ertredin in Human Hepatoma Cells As Revealed by Label-Free Chemical Proteomics

Park SI, Cho SM, Atsumi S, Kawada M, Shibuya M, Lee JY, Kim JY, Kwon HJ*

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Research

May 2023

J Clin Invest.

Volume 133, Issue 10

Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity.

Planas-Serra, L., Launay, N., Goicoechea, L., Heron, B., Jou, C., Juliá-Palacios, N., Ruiz, M., Fourcade, S., Casasnovas, C., De La Torre, C., Gelot, A., ... Pujol, A*. 

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Research

June 2023

iScience

Volume 26, Issue 7

A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts

Zhou M, Kong B, Zhang X, Xiao K, Lu J, Li W, Li M, Li Z, Ji W*, Hou J*, Xu T*.

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Research

July 2023

Int J Biol Sci

Volume 19, Issue 13

ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones

Tao S, Yang EJ, Zong G, Mou PK, Ren G, Pu Y, Chen L, Kwon HJ, Zhou J, Hu Z, Khosravi A, Zhang Q, Du Y, Shi WQ, Shim JS*

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Research

Jan 2023

Cell Rep.

Volume 42, Issue 1

The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria. 

Bassot, A., Chen, J., Takahashi-Yamashiro, K., Yap, M. C., Gibhardt, C. S., Le, G. N. T., Hario, S., Nasu, Y., Moore, J., Gutiérrez, T., Mina, L., Mast, H., ... Simmen, T*.

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Research

Aug 2023

Proc Natl Acad Sci USA.

Volume 120, Issue 32

Genome-wide kinase-MAM interactome screening reveals the role of CK2A1 in MAM Ca2+ dynamics linked to DEE66.

Thi My Nhung, T., Phuoc Long, N., Diem Nghi, T., Suh, Y., Hoang Anh, N., Jung, C. W., Minh Triet, H., Jung, M., Woo, Y., Yoo, J., Noh, S., Kim, S. J., Lee, S. B., ... Park, S. K*. 

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Research

Mar 2023

J Cell Biol.

Volume 222, Issue 3

PERK recruits E-Syt1 at ER-mitochondria contacts for mitochondrial lipid transport and respiration.

Sassano, M. L., van Vliet, A. R., Vervoort, E., Van Eygen, S., Van den Haute, C., Pavie, B., Roels, J., Swinnen, J. V., Spinazzi, M., ... , Felipe-Abrio, B., Agostinis, P*. 

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Research

Mar 2023

iScience.

Volume 26, Issue 4

Mitochondria-associated membrane protein PACS2 maintains right cardiac function in hypobaric hypoxia.

Yang, J., Sun, M., Chen, R., Ye, X., Wu, B., Liu, Z., Zhang, J., Gao, X., Cheng, R., He, C., He, J., Wang, X., Huang, L*.

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Research

Sep 2023

Cell Death Dis.

Volume 14, Issue 9

TGR5 supresses cGAS/STING pathway by inhibiting GRP75-mediated endoplasmic reticulum-mitochondrial coupling in diabetic retinopathy. 

Li, Y., Zhu, L., Cai, M. X., Wang, Z. L., Zhuang, M., Tan, C. Y., Xie, T. H., Yao, Y., & Wei, T. T*. 

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2023년

Research

Dec 2022

Cell Chem Biol

Volume 29, Issue 12

Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID

Kwak C, Park C, Ko M, Im CY, Moon H, Park YH, Kim SY, Lee S, Kang MG, Kwon HJ*, Hong E*, Seo JK*, Rhee HW*

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Research

Aug 2022

EMBO Rep.

Volume 23, Issue 10

UBXD8 mediates mitochondria-associated degradation to restrain apoptosis and mitophagy.

Zheng, J., Cao, Y., Yang, J., & Jiang, H*.

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Research

Sep 2022

Front Cell Dev Biol

Volume 10, Issue 918691

MFN2 mediates ER-mitochondrial coupling during ER stress through specialized stable contact sites.

Gottschalk, B., Koshenov, Z., Bachkoenig, O. A., Rost, R., Malli, R., & Graier, W. F*.

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Research

Jun 2022

Cell Chem Biol.

Volume 29, Issue 6

Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells. 

Miyake, M*., Sobajima, M., Kurahashi, K., Shigenaga, A., Denda, M., Otaka, A., Saio, T., Sakane, N., Kosako, H., & Oyadomari, S*. 

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Research

Apr 2022

Cancers

Volume 14, Issue 8

Mitochondrial ROS Produced in Human Colon Carcinoma Associated with Cell Survival via Autophagy

Gwak EJ, Kim D, Hwang HY, Kwon HJ*

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Research

Apr 2022

Clin Transl Med

Volume 13, Issue 1

Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via autophagy induction

Jung Y, Lee SE, Kang I, Cho SM, Kang KS, Kwon HJ*

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Research

Feb 2022

Nat Commun.

Volume 13, Issue 1

TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence.

Farfariello, V*., Gordienko, D. V., Mesilmany, L., Touil, Y., Germain, E., Fliniaux, I., Desruelles, E., Gkika, D., Roudbaraki, M., Shapovalov, G., ... ,Prevarskaya, N*.

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2023년

Research

Nov 2021

J Med Chem

Volume 64, Issue 21

Development of Novel VEGFR2 Inhibitors Originating from Natural Product Analogues with Antiangiogenic Impact

Cho SM, Kim Y, Jung Y, Ko M, Marko-Varga G, Kwon HJ*

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Research

Aug 2021

Clin Transl Med

Volume 11, Issue 8

Activation of Ca2+-AMPK-mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts

Kim D, Yang KE, Kim DW, Hwang HY, Kim J, Choi JS, Kwon HJ*

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Research

Sep 2021

Biochem Biophys Res Commun

Volume 568

 A natural small molecule induces MAPT clearance via mTOR-independent autophagy

Kim D, Hwang HY, Kwon HJ*

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